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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56df5678c2de8c7ca763b2804549d95180c86498f00e7a480eb6c829b7cea393' 
  AND token = 'IpgY9mFlS+NT9f+TeoMkLN8LgVUbRAeCOT0A9wBpCZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}