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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6889edf49c51401dbfd002167e5e66cfd922f6e63504619ee6b59f4216c60fc2' 
  AND token = 'On6we0HSYqPHpBgUyZym+b6+ojQXlXp/F2lmuC6dDa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}