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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b43de6d8cdd4850c614d50932e0be5644187d0f41b292d7f31ed42eefa4d79' 
  AND token = 'qVI5rRLERb8dpmnByFh82mnujztnJYyO/5yKDyVzqZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}