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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efca82c4fe2e8a31127f71a2ab8675a32240dc7a05a0866561570a82bea2eed' 
  AND token = '15QCmEoHI81/+rCEn9z3TZF1WGqttazfYxUGEUlMr+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}