SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bbd6b9da6b75e9c04ba408bda8054bfe48be787387fdc86b2a42fcd7bee1edc' 
  AND token = 'SBfViZLe3lcI5pKfyf9NlM42Qe4ze8Q3IaUu/tooqMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}