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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3250252b502dd810d356af2b88b9a175dc60dba5f82de11cb4e55cbd36530625' 
  AND token = 'buaeVtisrs2Tg45ol2ZD+8PBo+io8L29DXJXk/aqiqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}