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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79f89ac629b3215ea6c36ad06a5d8958ddf719aa110882107ffb27dff628b99f' 
  AND token = 'py5t+Vc+QiU0XCF8BsMeEEKeEqpMN9v9hPLhjDzjDXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}