SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f46dbcb92c2c675493bc12942e5fa23248b16bdc9807f62c95cb2b366197a276' 
  AND token = '6CnIqPEjHf9CFaw+ps8LE4TKlaFOJafl/UlYuJbfo18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}