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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8e3b22a7a7fff2f431133033c183de0a567a0569f8c10e52c75ec6d77033e4' 
  AND token = 'k+NP6sgeyn6FRmy/svRtX132tj/HzOjQnQzoRKyWN80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}