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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd981ad78f74f88b2920fa27aaab09643ccd35e5ec2b01874afb460f244aea8f8' 
  AND token = 'zQBMKh4JfOXrVfJdpo9T8+aPRMKi3zk48sXZ0P754o4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}