SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d0aecde6ac595f7627aa4311c60d0879dea5329fb3bad6baf17eacd0dbfe52' 
  AND token = 'er+ZLJBWn9qXaBqqPw0CBFrxqJlCm3ocy57Q67Z5Ywg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}