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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654b166a22e61a7a82b869cf731c0d75f472370d625c02286c76e562b6d60dbc' 
  AND token = 'xvoy0AwAzf8wkcKFpq+205opL6vsy9TRF84IIrebOM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}