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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd2c73bd42103c283569bc044022d69a4f518d0416880eda7ac7b2adf74d35ff' 
  AND token = '+tx1d/Se3MJS1iPxyr5KTDtXVTuVTlDtSIlbrbh0m/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}