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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80e0c982b3e9321153fb859d16c69804053bd8f982cd5e5c2d1f6785149e318' 
  AND token = 'owwt6cRE/rmxJjvUsgOsRM5TnKB/+MvL9EEEONibU2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}