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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61182ef29eedbcfbf7db03059b0491d83cf68744fc7ef3d97074925e9a20f7e4' 
  AND token = '5pToUFPTSwbgigY3ZE9hHFKoC9iU38hKCP+Y2oWLrbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}