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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5335abe611a84046abea5552b3ca448bc45971cca0d0190b5bf4241bd7a42e' 
  AND token = '3XfW8FfqlGnkeHQkVMn1DcjKa4lbJxZBQNMWqdPzIQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}