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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94e8516a456ed4cbbc7d57e88ee2c3ca19a423f845229d3370c8550bab691827' 
  AND token = 'k491emECrFMOF8uU48RC+kuJzV18r5uYk7x32iXYeU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}