SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63ae0b6027f7c5c22cbdb3d496864869e3e89642dbb9d44324da86e39c3237f8' 
  AND token = 't+VpI44KGYO2KHNbz6h0iq7iQbFWRrIKT46ZFNcNAA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}