SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41b11b46974992e88f3b401f572e594abcb025bf7e21417ed27fbff6eb7406d' 
  AND token = 'yRpCWoJJtuqDfqNEihV6f3U0diAkBCtC2Zm4/ocNW3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}