SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a21e6e9040ec8a9ccd25fc9fd4f6e9b6ac25fa18e1f519ca80497c052bac7c4' 
  AND token = 'u8AoKBqI21BQIu8hsw+5Yp231uEG/czqE6911wR2Vjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}