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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e37f47632d9d2c7ba466964a5890cef8ad5cad170b0d3f98cd619e3b960295e' 
  AND token = 'qqwl3Bt5XnAANjlmZnpS4LRyBBAG/CldXMLB1n68mFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}