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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae7caa04906a4429d4f1de39a8ce0aeb99594994baf5edf236a73ff310324d3' 
  AND token = '8eDZrFe0/cybVbz4gyB9XvYO4ZgsYsMDjyE646+4zMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}