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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a37dbc52c22a291152c4848ecab2475cb64dd75ecb9b4ff0cc84d3f182b3102' 
  AND token = '8S4iQCrBhzfFzoYD1gHingm4Nhmpk5t1pwuOZb6O7Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}