SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4184ad36a0153769211b2e7d3fe61c14ef228ada7d8a8be15090bf3a8e7acfa' 
  AND token = 'Uz1a8retcrpDcyhSzJByJE4eHzlxiClnMsAj01BNENk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}