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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7858643c4af79cd7c17b38d006cb64fdf638f4c971b80eb3af6eb21b41e8d0' 
  AND token = 'Mz9rG+vTU5SQVQH25RkWehK9Ne1uULS/+Bu/8ZcT++M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}