SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6abfd1e24d6810f6560a20dbf147f7fd42f17cc0bb3359b92810d773c838408' 
  AND token = 'A5VrbtYh41fCknGTFEZi3lqKiYNgiOPfqcT/0uMHRbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}