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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92461d254639a3187cba7a1ea262e9471d4bf00978195e5b89fc97d516016cfb' 
  AND token = 'aPGXw/jvp8T1faQ8MNNKrB3xnRZKWJrb0FYNSLaEMQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}