SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a214f9d1743c487ed5dd2b495a5930d7c8a8a76327726a59b082cd585187aea' 
  AND token = '1yar1zWyQtKvgdiTyO+piH6rTk5akIHhSXsDdoIG0VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}