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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c5eed7e477a0f1ae5c4f02fab1883c94c7fdd90b2ca2a08a0f1fe2dbe25734' 
  AND token = 'MmqQrSxJvl6O5jDj9hxurwThiy+ce/PWbOj8q2REZHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}