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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f26b2a6c068817978361b21d4b0e173e28a3189b374d3b5d9cd1d328b239bb3' 
  AND token = '7f2SQTUDIUOGU+HUMzNVXZ9zAGrHzrt7An4uPTAFU3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}