SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0051c7cb41e263d8c881991c4823fd96c6d0a5f73770688735ebe708117796' 
  AND token = 'rWvuAc5NYu8iR/S2CtdwbZ9T5xmtdI8weqc1zt+NKIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}