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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1740708e89c82e3519f6745d59ff2a2c0b07dcf7a75611eedbbc411934db5f09' 
  AND token = 'iHwoT9nKeMtAr/OYEAGtdv9i3h5Nv/iNjz6yan0t7Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}