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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0321cabfd4c61d47b10c62cb852e8b08b9e23160499b0066b5093f54230cdbff' 
  AND token = 'KrSJTij5VpYqnXpkH2c9FmCU1D+kD72+EKTSZQ55NVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}