SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2bc278d8d076bedcac8347990f59feac4fff5ce6c82627021a8deb4359a46a1' 
  AND token = 'Q40ZsWcUC2Nv+p1OXcAKZaiSz8bzPYnX8ejvlWbyYXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}