SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb0c6676d0d7cb2047cc8a9521ac328b1439b480be9d5ee9b1134406a84f66b' 
  AND token = '1IY9IVUWb6dGGHiHFswcb8vvJdENnu/PvjA/PA2FFZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}