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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3db71b8f78611b3495fc1400c77a786ead2fe06b80cd071fb5bc71ea50eae4' 
  AND token = 'BtAGWQc4pBpKBiKgMBWuUzUz1zXfw8TmEQdFxWHqN5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}