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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec3795cbfdb27017ba87a9f8195b98f528d193a954b0081849fc09c0fe9d262' 
  AND token = 'sEAhZbDMyLZ/wrcm3vAM9S3p6d2EIKvsIoCM0412Rms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}