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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f107679e806fd2c9035cd606f7c626441560b9022b1e6a76f055fbd2e06d457' 
  AND token = '2xMwmCRRIqt5xjpAR91ddZrf2Xn+9pFCwWbRSX1Y0LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}