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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921dbbf7792e0159ccbf6daabe03ac27d47c6f4403aea07d45f0dd8592c522f5' 
  AND token = 'nYR2P6D0GPcekKGX5l7MIZ4AiZShv3WtyFwEtaY+q2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}