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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb8ac5d12200324bf3d433efffc2e310e96936da7a445bbd24608c408bb0448' 
  AND token = 'DAZtxny7hzlKI6f9HvJaJimpv+GfypACSOkkzbU1frk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}