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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52e83efd809cec3787204d6533fbd33b7586b773cb718351b69c54c1237ca2b' 
  AND token = 'iUnA6KzhdSDdGhqu6R7a5sbcKXg0Qup4IVA/oa/qCnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}