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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e30e98aaaa6f5ad697e26916d2b3b6ecbd86eedfba2da93706bb9a82c7c5ba' 
  AND token = '7TDV3eVTbqhEx3ZBwV7J1SJNxZDa6ZeCMm72wvEcmp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}