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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd309638353702bd6d2be5c7d80a0e9f76541c4b2c3e4631ae1e83d874cce6d4f' 
  AND token = 'jHyN9bNWvCTUscRvDJ0Psdgk1TZVDHvEEIVnLLg2lpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}