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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12919741ae107bf93b584a10dcec70c2402ce3e4d3c8b5aa1c88f843b823f384' 
  AND token = 'DwNhSLmDKH5x2GGXT4fXXCj3FWCvPq1utt/rJIhDfdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}