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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b2f1331d1c80eebfb4263f9f80d5723304686e6605063494cac56d3a5a449a' 
  AND token = 'hhq0DukuuIyrH4Sd316UD36PZ5GX0ffFyGtXDEt/sMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}