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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7288dd68d5d1f7e5faf27df5bb9c0a1b5d2d3f87845146fdc3f5550dd1101b69' 
  AND token = 'E6MwfOVgnt+MjitftLU/k/UJ2JlFagB3h7+9FKOYeUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}