SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561a84d44dc832ba45927fa99435dd0b572f7675aabdcb2d2bbb049269522416' 
  AND token = 'ovPyRd2XjyWgsUj10KZH27uiAC9xx37DQOWzsEoJmaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}