SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67039f6a51d183923f774a19390ec517d528e886dc6cea5b4c2b29e845c58e09' 
  AND token = 'YzSYwSPGG7gU4U0vcSTf32VVQmNX3c5TOsRCHsgyN18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}