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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382581fdb630bce56dad98c1bdab93bc9133e16f9f94e0dc22f664408e1def65' 
  AND token = '5J05eH/AmPpiZOjeYkJ9lkjKsN8nl9u51Qi/Cg/5Y5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}