SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4659404e0b4d7b9e0cec1940730211dbfcbc52e4ab915eee50be05af01abbdf8' 
  AND token = 'oXTpLfAXUTRa/QvgLT3yi3TenOn1hdVe1QJRnRRiV/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}